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Nitrogenous bases covalently linked to a sugar with and without phosphate groups; used for synthesis, cell signaling, and as cofactors in enzymatic reactions; includes pyrimidine, purine, pyridine, flavin, pyrrolopyrimidine, and triazole varieties.
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4-Thio-2'-deoxyuridine is a sulfur-substituted deoxyuridine nucleoside analogue used in biochemical and nucleic acid research, including studies of nucleic acid chemistry and incorporation into oligonucleotides. It has molecular formula C9H12N2O4S, molecular weight 244.27 g/mol, and a reported purity of 99.78%.
Sulfur-substituted deoxyuridine analogue useful for nucleic acid studies.
High reported purity (99.8%), suitable for analytical and synthetic applications.
Available in multiple pack sizes for research-scale work.
Provided with certificate of analysis and safety data sheet for quality and handling.
Offered in solid form and as 10 mM DMSO solution for convenient use.
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2'-Deoxycytidine, a deoxyribonucleoside, can inhibit the biological effects of Bromodeoxyuridine (Brdu). It is essential for the synthesis of nucleic acids and can be used for cancer research.
Deoxyribonucleoside
Inhibits biological effects of bromodeoxyuridine (Brdu)
Essential for the synthesis of nucleic acids
Can be used for cancer research
Inhibits tumor growth in mice
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
KTX-951 is an orally active PROTAC degrader targeting IRAK4 and IMiD (Ikaros/Aiolos) substrates. It demonstrates potent DC50s against IRAK4, Ikaros, and Aiolos, and exhibits antitumor activity with an IC50 of 35 nM for OCl-Ly10 CTG.
Orally active PROTAC degrader
Targets IRAK4 and IMiD substrates (Ikaros/Aiolos)
Potent DC50s for IRAK4, Ikaros, and Aiolos
Exhibits antitumor activity
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5-Chloro-2 -deoxyuridine (CAS No 50-90-8) is a nucleoside analog commonly used in biomedical research especially in studies related to DNA synthesis and repair mechanisms Originating from modified pyrimidine derivatives it incorporates into DNA and interferes with replication leading to the inhibition of cellular proliferation Its mechanism of action involves targeting the DNA polymerase pathways making it effective in various experimental models In vitro it exhibits activity in the nanomolar to low micromolar range This compound is frequently employed in cancer research particularly in cell culture models and animal studies to assess its potential as a chemotherapeutic agent It s also used in drug screening assays to evaluate novel drug interactions and efficacy Experimental concentrations typically depend on the specific research design allowing flexibility for researchers to tailor their studies according to their unique objectives and model systems
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